BIOPEP-UWM: Report

ID 586
Name Hyaluronidase inhibitor
sequence
GDKGE

Function:
Predicted inhibitor of Hyaluronidase (EC 3.2.1.35) (PDB: ID 2PE4)
 
Number of residues
5
Activity code
hyal
Activity :
Hyaluronidase inhibitor
Chemical mass 504.4903 Monoisotopic mass 504.2172
EC50 :
0.00 µM



Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C19H32N6O10/c20-6-2-1-3-10(25-18(33)12(7-16(30)31)24-13(26)8-21)17(32)22-9-14(27)23-11(19(34)35)4-5-15(28)29/h10-12H,1-9,20-21H2,(H,22,32)(H,23,27)(H,24,26)(H,25,33)(H,28,29)(H,30,31)(H,34,35)/t10-,11-,12-/m0/s1

InChIKey=KVLCNRNHMMIQEB-SRVKXCTJSA-N

Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I) according to the BIOPEP-UWM Virtual database
Predicted inhibitor of Tyrosinase (EC 1.14.18.1) (PDB ID: 2Y9X) according to the BIOPEP-UWM Virtual database



Database reference: