BIOPEP-UWM: Report

ID 606
Name ACE inhibitor
sequence
QSW

Function:
Predicted inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 419.4307 Monoisotopic mass 419.1799
EC50 :
0.00 µM



Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C19H25N5O6/c20-12(5-6-16(21)26)17(27)24-15(9-25)18(28)23-14(19(29)30)7-10-8-22-13-4-2-1-3-11(10)13/h1-4,8,12,14-15,22,25H,5-7,9,20H2,(H2,21,26)(H,23,28)(H,24,27)(H,29,30)/t12-,14-,15-/m0/s1

InChIKey=QENSHQJGWGRPQS-QEJZJMRPSA-N


Activity predicted using QSAR


Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 55)



Database reference:
BIOPEP-UWM Virtual database: ID 55

ChEBI: ID 162488

ChemSpider: ID 61710871

J-GLOBAL: ID 200907062591753202

Metabolomics Workbench: ID 81373

MMDB: ID 128381

Nikkaji: ID J2.110.552J

PubChem: CID 91667417

UniChem: ID 97534941

Wikidata: ID Q76805839