BIOPEP-UWM: Report

ID 612
Name ACE inhibitor
sequence
PGPI
Function:
Predicted inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 382.4534 Monoisotopic mass 382.2209
EC50 :
0.00 µM


Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C18H30N4O5/c1-3-11(2)15(18(26)27)21-17(25)13-7-5-9-22(13)14(23)10-20-16(24)12-6-4-8-19-12/h11-13,15,19H,3-10H2,1-2H3,(H,20,24)(H,21,25)(H,26,27)/t11-,12-,13-,15-/m0/s1

InChIKey=BMXYUOXPDHJSBM-ABHRYQDASA-N


Activity predicted using QSAR


Database reference:
ChemSpider: ID 8493223

PubChem: CID 10317759