BIOPEP-UWM: Report

ID 633
Name ACE inhibitor
sequence
LT
Function:
Predicted inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 232.2760 Monoisotopic mass 232.1418
EC50 :
0.00 µM


Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM Virtual database



SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O

InChI=1S/C10H20N2O4/c1-5(2)4-7(11)9(14)12-8(6(3)13)10(15)16/h5-8,13H,4,11H2,1-3H3,(H,12,14)(H,15,16)/t6-,7+,8+/m1/s1

InChIKey=LRKCBIUDWAXNEG-CSMHCCOUSA-N


Activity predicted using QSAR


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8824); the DFBP database
Hypouricemic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10741)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10749)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8824; 10741; 10749

BRENDA: Ligand L-leucyl-L-threonine

ChEBI: ID 73589

ChemSpider: ID 8529330

DFBP: ID DFBPANOX0599

EROP-Moscow: ID E01610

FooDB: ID FDB111963

HMDB: ID HMDB0028939

J-GLOBAL: ID 202307009512758662

Metabolights: ID MTBLC73589

Metabolomics Workbench: ID 78872

Nikkaji: ID J3.790.788J

NMRShiftDB: ID 60023641

PlantPepDB: ID PPepDB_3464

PubChem: CID 10353878

SCHOLIA: ID Q27141903

SureChEMBL: ID SCHEMBL8527776

UniChem: ID 26825780

Wikidata: ID Q27141903