BIOPEP-UWM: Report

ID 64
Name Antiviral peptide
sequence
LGY

Function:
Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7)
 
Number of residues
3
Activity code
avi
Activity :
antiviral
Chemical mass 351.3965 Monoisotopic mass 351.1788
EC50 :
0.00 µM



Bibliographic data:
Authors
Behzadipour Y., Gholampour M., Pirhadi S., Seradj H., Khoshneviszadeh M., Hemmati S.
Title
Viral 3CLpro as a target for antiviral intervention using milk‑derived bioactive peptides. Int. J. Pept. Res. Therapeut., 27, 2703–2716, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C17H25N3O5/c1-10(2)7-13(18)16(23)19-9-15(22)20-14(17(24)25)8-11-3-5-12(21)6-4-11/h3-6,10,13-14,21H,7-9,18H2,1-2H3,(H,19,23)(H,20,22)(H,24,25)/t13-,14-/m0/s1

InChIKey=UCDHVOALNXENLC-KBPBESRZSA-N


Bioactivity predicted using molecular docking

Immunostimulating peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3099)
Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9284); the MBPDB database
Peptide regulating phosphoinositol metabolism according to the BIOPEP-UWM database of bioactive peptides (ID 2738)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10060)




Database reference:
BIOPEP-UWM database of bioactive peptides: ID 2738; 3099; 9284; 10060

ChemSpider: ID 5377958

EROP-Moscow: ID E09276

FeptideDB: ID 2738; 3099

MBPDB: Peptide LGY

PubChem: CID 7014904