BIOPEP-UWM: Report

ID 668
Name Alpha-amylase inhibitor
sequence
IEFGN
Function:
Inhibitor of alpha-amylase (EC 3.2.1.1) (PDB: ID 4W93)
 
Number of residues
5
Activity code
aami
Activity :
alpha-amylase inhibitor
Chemical mass 578.6132 Monoisotopic mass 578.2691
EC50 :
0.00 µM


Bibliographic data:
Authors
Manzanilla-Valdez M. L., Montaño S., Martinez-Villaluenga C., Zúñiga F., Boesch C., Hernandez-Alvarez A. J.
Title
Antioxidant, hypotensive, and antidiabetic breakthroughs: bromelain hydrolysis unlocks quinoa’s peptide potential - in silico and in vitro approach. J. Agric. Food Chem., 73, 22877−22894, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)NCC(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C26H38N6O9/c1-3-14(2)22(28)25(39)31-16(9-10-21(35)36)24(38)32-17(11-15-7-5-4-6-8-15)23(37)29-13-20(34)30-18(26(40)41)12-19(27)33/h4-8,14,16-18,22H,3,9-13,28H2,1-2H3,(H2,27,33)(H,29,37)(H,30,34)(H,31,39)(H,32,38)(H,35,36)(H,40,41)/t14-,16-,17-,18-,22-/m0/s1

InChIKey=BFUKRLNZPARSQQ-UGCUYICYSA-N


Activity predicted using molecular docking


Database reference: