BIOPEP-UWM: Report

ID 7
Name Anticancer peptide
sequence
FGPEMEQ

Function:
Predicted ligand of Keap1 protein (PDB ID: 2FLU)
 
Number of residues
7
Activity code
ac
Activity :
anticancer
Chemical mass 836.9079 Monoisotopic mass 836.3362
EC50 :
0.00 µM



Bibliographic data:
Authors
Chai T.-T., Koh J.-A., Wong C. C.-C., Sabri M.Z., Wong F.-C.
Title
Computational screening for the anticancer potential of seed-derived antioxidant peptides: a cheminformatic approach. Molecules, 26, 7396, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C31H47N11O11/c1-15(2)6- InChI=1S/C36H52N8O13S/c1-58-17-15-24(34(54)40-22(10-13-29(47)48)33(53)43-25(36(56)57)9-12-27(38)45)41-32(52)23(11-14-30(49)50)42-35(55)26-8-5-16-44(26)28(46)19-39-31(51)21(37)18-20-6-3-2-4-7-20/h2-4,6-7,21-26H,5,8-19,37H2,1H3,(H2,38,45)(H,39,51)(H,40,54)(H,41,52)(H,42,55)(H,43,53)(H,47,48)(H,49,50)(H,56,57)/t21-,22-,23-,24-,25-,26-/m0/s1 20(29(50)42-22(31(52)53)8-18-10-34-14-37-18)40-30(51)23(12-43)38-24(44)11-35-27(48)21(7-17-9-33-13-36-17)41-28(49)19(4-5-25(45)46)39-26(47)16(3)32/h9-10,13-16,19-23,43H,4-8,11-12,32H2,1-3H3,(H,33,36)(H,34,37)(H,35,48)(H,38,44)(H,39,47)(H,40,51)(H,41,49)(H,42,50)(H,45,46)(H,52,53)/t16-,19-,20-,21-,22-,23-/m0/s1

InChIKey=XNPCGUYELQRKKY-FRSCJGFNSA-N


Bioactivity predicted using molecular docking



Database reference: