BIOPEP-UWM: Report

ID 8
Name Anticancer peptide
sequence
PSYLNTPLL

Function:
Predicted ligand of Keap1 protein (PDB ID: 2FLU)
 
Number of residues
9
Activity code
ac
Activity :
anticancer
Chemical mass 1017.1726 Monoisotopic mass 1016.5524
EC50 :
0.00 µM



Bibliographic data:
Authors
Chai T.-T., Koh J.-A., Wong C. C.-C., Sabri M.Z., Wong F.-C.
Title
Computational screening for the anticancer potential of seed-derived antioxidant peptides: a cheminformatic approach. Molecules, 26, 7396, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C48H76N10O14/c1-24(2)18-31(51-43(66)33(21-28-12-14-29(61)15-13-28)52-45(68)36(23-59)56-40(63)30-10-8-16-50-30)41(64)53-34(22-38(49)62)44(67)57-39(27(7)60)47(70)58-17-9-11-37(58)46(69)54-32(19-25(3)4)42(65)55-35(48(71)72)20-26(5)6/h12-15,24-27,30-37,39,50,59-61H,8-11,16-23H2,1-7H3,(H2,49,62)(H,51,66)(H,52,68)(H,53,64)(H,54,69)(H,55,65)(H,56,63)(H,57,67)(H,71,72)/t27-,30+,31+,32+,33+,34+,35+,36+,37+,39+/m1/s1

InChIKey=PTUDEFPJGDGLOJ-WIIVDTJVSA-N


Bioactivity predicted using molecular docking



Database reference: