Untitled Document

BIOPEP-UWM: Peptide Data

ID		Name
Sequence	RF
	RF

Chemical Mass		Number of residues
Monoisotopic Mass			µM

Additional Information

BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C15H23N5O3/c16-11(7-4-8-19-15(17)18)13(21)20-12(14(22)23)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H,20,21)(H,22,23)(H4,17,18,19)/t11-,12-/m0/s1

InChIKey: PQBHGSGQZSOLIR-RYUDHWBXSA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Another value of peptide IC50(EC50)=230 uM

Cushman D. W., 1981. Angiotensin converting enzyme inhibitors:Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg.

Peptide found also in amaranth protein hydrolysate.

Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111

Inhibitor of UBR protein in rabbit reticulocyte lysates according to the PubChem database
Inhibitor of dipeptidyl peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9490); the BRENDA database
Inhibitor of leucyltransferase (EC 2.3.2.6) according to the BRENDA database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 13)

Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 62)

screen and print peptide data

list of peptides

Bioactive peptides links	BIO 9490	BIO 10547
Sensory peptides and amino acids links	Sens 13
Virtual peptides links	Virt 62