BIOPEP-UWM: Peptide Data
ID
Name
Sequence
AY
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O InChI=1S/C12H16N2O4/c1-7(13)11(16)14-10(12(17)18)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)/t7-,10-/m0/s1 InChIKey=ALZVPLKYDKJKQU-XVKPBYJWSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Another value of peptide IC50(EC50) = 88uM Cushman D. W., 1981. Angiotensin converting enzyme inhibitors: Evolution of a new class of antihypertensive drugs (page 19). in: Horovitz Z. P. (Ed.)(1981), Mechanisms of action and clinical implications, Urban & Schwarzenberg. Found in amaranth (Amarantus hypochondriacus) protein hydrolysate: Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Found in Okara, by-product obtained during the manufacturing of soymilk and tofu. Yokomizo A., Takenaka Y., Takenaka T., 2002, Antioxidative activity of peptides prepared from Okara protein. Food Sci. Technol. Res., 8, 357-359 Found in corn milling byproducts. Lin F., Chen L., Liang R., Zhang Z., Wang J., Cai M., Li Y., 2011, Pilot-scale production of low molecular weight peptides from corn wet milling byproducts and the antihypertensive effects in vivo and in vitro. Food Chem., 124, 801-807 Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 7866) Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8765) Inhibitor of Tubulin-tyrosine ligase (EC 6.3.2.25) according to the BIOPEP-UWM database of bioactive peptides, the BRENDA database
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