BIOPEP-UWM: Peptide Data
ID
Name
Sequence
GP
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
IC50
µM
Additional Information
BIOPEP-UWM database of bioactive peptides SMILES: C1C[C@H](N(C1)C(=O)CN)C(=O)O InChI=1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)/t5-/m0/s1 InChIKey: KZNQNBZMBZJQJO-YFKPBYRVSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Another value of peptide IC50 (EC50) = 450 uM Meisel H., Walsh D. J., Murray B., FitzGerald R. J., 2006. ACE inhibitory peptides. In: Nutraceultical Proteins and Peptides in Health and Disease. Taylor and Francis Group, Boca Raton, London, New York, 269-315. Another value of peptide IC50 (EC50) = 360 uM Ichimura T., Yamanaka A., Otsuka T., Yamashita E., Maruyama S., 2009, Antihypertensive effect of enzymatic hydrolysate of collagen and Gly-Pro in spontaeously hypertensive rats. Biosci. Biotech. Biochem., 73, 2317-2319 Reveals activity in vivo in spontaneously hypertensive rats. Ichimura T., Yamanaka A., Otsuka T., Yamashita E., Maruyama S., 2009, Antihypertensive effect of enzymatic hydrolysate of collagen and Gly-Pro in spontaeously hypertensive rats. Biosci. Biotech. Biochem., 73, 2317-2319 Inhibitor of dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 3169); Antithrombotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3283); Inhibitor of prolyl endopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001) according to the BIOPEP-UWM database of bioactive peptides (ID 3461) Regulator of the stomach mucosal membrane activity according to the BIOPEP-UWM database of bioactive peptides (ID 2753) Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids, the ChEMBL database; the EROP-Moscow database (ID E03695), the PubChem database
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