NameLinkDescription
BRENDAhttp://www.brenda-enzymes.org/Database of enzymes containing the information about optimal conditions of enzyme action.
CaspNeuroDhttp://caspdb.sanfordburnham.org/caspneurod.phpDatabase of predicted caspase cleavage sites in human proteins, associated with neurodegenerative diseases
CutDBhttp://cutdb.burnham.orgDatabase of specificity of less-known endopeptidases.
DeepCleavehttps://deepcleave.erc.monash.edu/Program predicting specificity of caspases.
Degradome databasehttp://degradome.uniovi.esDatabase of mammalian (e.g. human) proteolytic enzymes
ECPredhttp://ecpred.kansil.org/Program for enzyme function prediction
EnzymeDetectorhttp://enzymedetector.tu-bs.de/Database providing overview of the available enzyme function annotations (including proteolytic ones) for a genome of interest
EnzymeMinerhttps://loschmidt.chemi.muni.cz/enzymeminer/Program predicting enzymatic (e.g. proteolytic) activity of proteins.
Enzyme Predictorhttp://bioware.ucd.ie/~enzpred/Enzpred.phpProgram predicting specificity of proteolytic enzymes
ExplorEnzhttp://www.enzyme-database.orgDatabase of enzymes e.g. proteolytic
FunTreehttp://www.ebi.ac.uk/thornton-srv/databases/FunTree/Database designed for classification of enzyme superfamilies including proteolytic enzymes
HIVcleavehttp://chou.med.harvard.edu/bioinf/HIV/Program designed for prediction of HIV proteases cleavage sites in proteins and peptides.
MEROPShttp://merops.sanger.ac.uk/Database of proteolytic enzymes.
NeuroPredhttp://neuroproteomics.scs.uiuc.edu/neuropred.htmlPrediction of sites of cleavage leading to the release of neuropeptides.
Open Targetshttps://www.targetvalidation.org/Database providing information about association of enzymes (including proteolytic) with diseases
PCSShttps://www.targetvalidation.org/Database providing information about association of enzymes (including proteolytic) with diseases
PepCleave IIhttp://peptibase.cs.biu.ac.il/PepCleave_II/Program predicting peptides resulting from proteasome cleavage
Peptide-Cutterhttp://www.expasy.org/tools/peptidecutter/Program for proteolysis simulation.
PeptideMaphttp://prowl.rockefeller.edu/prowl/peptidemap.htmlProgram for proteolysis simulation and calculation of masses of resulting peptides
PMAPhttp://www.proteolysis.orgDatabase of proteolytic events
POPShttp://pops.csse.monash.edu.au/pops-cgi/index.phpPrediction of proteolytic cleavage sites
Protease Classification Systemhttp://pcal.biosino.org/protease_classification.htmlClassification of proteolytic enzymes on the basis of amino acid sequences
Promishttp://web.issb.genopole.fr/~faulon/promis.phpProgram predicting enzyme promiscuity based on molecular signatures. May be applied e.g. to proteolytic enzymes
Proteolytic Enzymes Databasehttp://www.proteolyticenzymes.infoDatabase of proteolytic enzymes
ProtIdenthttp://www.csbio.sjtu.edu.cn/bioinf/Protease/Program classifying uncharacterized proteins as proteases or non-proteases and predicting possible action mechanism on the basis of amino acid sequences
SitePredictionhttp://www.dmbr.ugent.be/prx/bioit2-public/SitePrediction/Program predicting sites suceptible for proteolytic cleavage
SpirPephttp://spirpepapp.sbi.kmutt.ac.th/SpirPep/Program for proteolysis simulation linked to metabase of bioactive peptides