Name	Link	Description
BENZ WS	https://benzdb.biocomp.unibo.it/	Program assigning protein to enzyme class on the basis of sequence
BRENDA	http://www.brenda-enzymes.org/	Database of enzymes containing the information about optimal conditions of enzyme action
CaspNeuroD	http://caspdb.sanfordburnham.org/caspneurod.php	Database of predicted caspase cleavage sites in human proteins, associated with neurodegenerative diseases
CutDB	http://cutdb.burnham.org	Database of specificity of less-known endopeptidases
DeepCleave	https://deepcleave.erc.monash.edu/	Program predicting specificity of caspases.
Degradome database	http://degradome.uniovi.es	Database of mammalian (e.g. human) proteolytic enzymes
ECPred	http://ecpred.kansil.org/	Program for enzyme function prediction
EnzymeDetector	http://enzymedetector.tu-bs.de/	Database providing overview of the available enzyme function annotations (including proteolytic ones) for a genome of interest
EnzymeMiner	https://loschmidt.chemi.muni.cz/enzymeminer/	Program predicting enzymatic (e.g. proteolytic) activity of proteins.
Enzyme Predictor	http://bioware.ucd.ie/~enzpred/Enzpred.php	Program predicting specificity of proteolytic enzymes
ExplorEnz	http://www.enzyme-database.org	Database of enzymes e.g. proteolytic
FunTree	http://www.ebi.ac.uk/thornton-srv/databases/FunTree/	Database designed for classification of enzyme superfamilies including proteolytic enzymes
HIVcleave	http://chou.med.harvard.edu/bioinf/HIV/	Program designed for prediction of HIV proteases cleavage sites in proteins and peptides
MEROPS	http://merops.sanger.ac.uk/	Database of proteolytic enzymes
NeuroPred	http://neuroproteomics.scs.uiuc.edu/neuropred.html	Prediction of sites of cleavage leading to the release of neuropeptides
Open Targets	https://www.targetvalidation.org/	Database providing information about association of enzymes (including proteolytic) with diseases
PCPS	http://imed.med.ucm.es/Tools/pcps/	Program predicting proteasome cleavage sites
PCSS	https://www.targetvalidation.org/	Database providing information about association of enzymes (including proteolytic) with diseases
PepCleave II	http://peptibase.cs.biu.ac.il/PepCleave_II/	Program predicting peptides resulting from proteasome cleavage
Peptide-Cutter	http://www.expasy.org/tools/peptidecutter/	Program for proteolysis simulation.
PeptideMap	http://prowl.rockefeller.edu/prowl/peptidemap.html	Program for proteolysis simulation and calculation of masses of resulting peptides
PMAP	http://www.proteolysis.org	Database of proteolytic events
POPS	http://pops.csse.monash.edu.au/pops-cgi/index.php	Prediction of proteolytic cleavage sites
Protease Classification System	http://pcal.biosino.org/protease_classification.html	Classification of proteolytic enzymes on the basis of amino acid sequences
Promis	http://web.issb.genopole.fr/~faulon/promis.php	Program predicting enzyme promiscuity based on molecular signatures. May be applied e.g. to proteolytic enzymes
Proteolytic Enzymes Database	http://www.proteolyticenzymes.info	Database of proteolytic enzymes
ProtIdent	http://www.csbio.sjtu.edu.cn/bioinf/Protease/	Program classifying uncharacterized proteins as proteases or non-proteases and predicting possible action mechanism on the basis of amino acid sequences
SitePrediction	http://www.dmbr.ugent.be/prx/bioit2-public/SitePrediction/	Program predicting sites suceptible for proteolytic cleavage
SpirPep	http://spirpepapp.sbi.kmutt.ac.th/SpirPep/	Program for proteolysis simulation linked to metabase of bioactive peptides